Christian McCaffrey and 49ers Favored to Dominate Cardinals

  • The San Francisco 49ers are 14.0-point favorites against the Arizona Cardinals at home.
  • San Francisco won their last 14 games as a 14.0-point favorite or greater.
  • The 49ers are the favorites to win Super Bowl 58 at +550.

SAN FRANCISCO – The Arizona Cardinals are 14.0-point underdogs to the San Francisco 49ers despite winning outright against the Dallas Cowboys in Week 3. Dallas had -800 moneyline odds to win the game, but it’s unlikely the 49ers meet the same fate with their -900 moneyline odds.

The San Francisco 49ers are the current favorite for betting on the Super Bowl with +550 odds. Arizona is tied with the Houston Texans for the longest odds to win SBLVIII.

The NFC West battle between Arizona and San Francisco has -110 odds to go over 44.0 total points.

San Francisco 49ers vs Arizona Cardinals Betting Lines

Team Spread Moneyline Total
Arizona Cardinals +14.0 (-110) +575 O44.0 (-110)
San Francisco 49ers -14.0 (-110) -900 U44.0 (-110)

Their last three head-to-head matchups went over the 44.0-point total. San Francisco covered a 14.5-point spread in each of their last two matchups, wining by a combined 53 points.

The 49ers Super Bowl 58 odds are favored as a result of an excellent defense and Christian McCaffrey. McCaffrey has 423 total yards and three touchdowns in three games this season.

Christian McCaffrey Rushing Projection

His rushing yards projection has -120 odds to go under 81.5 rushing yards in Week 4. McCaffrey went over 80.5 rushing yards in all three games this season.

Christian McCaffrey Rushing Yards Projection

  • Over 81.5 Rushing Yards -110
  • Under 81.5 Rushing Yards -120

His 85-yard performance in Week 3 marked his first game with less than 116 rushing yards. As long as the 49ers don’t bench McCaffrey early, he should clear the 81.5-yard projection with ease.

Tony Pollard rushed for 122 yards on the Cardinals defense in Week 3. Their poor run defense has the Cardinals Super Bowl 58 odds at +45000 to make a miracle Super Bowl run this season.

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